Publicações
A comunicação dos resultados da nossa investigação é fundamental. Esta preocupação reflete-se no nível de publicações em jornais e revistas com fator de impacto e no número de pósteres e apresentações nos principais congressos mundiais, particularmente nas neurociências.
Consulte abaixo exemplos de publicações, alguns de autoria ou co-autoria de cientistas BIAL.
Acetato de Eslicarbazepina
Trinka E, Ben-Menachem E, Kowacs PA, Elger C, Keller B, Löffler K, et al.
Published: Epilepsia [Internet]. 2018;59(2):479–91.
Costa R, Steinhoff B, Gama H, Ikedo F, Rocha JF, Soares-da-Silva P. Safety, Tolerability and Efficacy of Eslicarbazepine
Published: Drugs Aging [Internet]. 2018;
Jóźwiak S, Veggiotti P, Moreira J, Gama H, Rocha F, Soares-da-Silva P.
Published: Epilepsy & behavior : E&B [Internet]. 2018;81:1–11.
Sperling MR, Abou-Khalil B, Harvey J, Rogin JB, Biraben A, Galimberti CA, et al..
Published: Epilepsia [Internet]. 2015;56(2):244–53.
Opicapona
Ferreira JJ, Lees A, Rocha JF, Poewe W, Rascol O, Soares-da-Silva P.
Published: Eur J Neurol [Internet]. 2019;null–null.
Ferreira JJ, Lees AJ, Poewe W, Rascol O, Rocha JF, Keller B, et al.
Published: Neurology [Internet]. 2018;90(21):e1849–e1857.
Rocha JF, Falcão A, Santos A, Pinto R, Lopes N, Nunes T, et al.
Published: Eur J Clin Pharmacol [Internet]. 2014;70(9):1059–71.
Lees AJ, Ferreira J, Rascol O, Poewe W, Rocha JF, McCrory M, et al.
Published: JAMA Neurol [Internet]. 2017;74(2):197–206.
Zamicastat
Effect of zamicastat in chronic treatment on right ventricle pressure overload in the rat monocrotaline lung injury model of pulmonary hypertension
Igreja, B., Pires, N., Moser, P. and Soares-da-Silva, et al.
Published: Hypertension. 2016;68(Suppl. 1: AP238).
Effect of Chronic Treatment With Zamicastat on Right Ventricle Pressure Overload in the Rat Monocrotaline Lung Injury Model of Pulmonary Hypertension.
Igreja, B., Pires, N., Moser, P. and Soares-da-Silva, et al.
Published: The FASEB Journal. 2017;31(1 Supplement 1070.7).
Effect of zamicastat, a dopamine beta-hydroxylase inhibitor, on the monocrotaline rat model of pulmonary arterial hypertension.
Moura, E., Costa, C., Igreja B., Pires, et al.
Published: European Respiratory Society Meeting. 2020.
The Dopamine Beta-Hydroxylase Inhibitor Zamicastat Improves Survival in the Rat Monocrotaline Model of Pulmonary Arterial Hypertension.
Bonifacio M.J., Moura E., Sousa F., Igreja B., Pires N., Soares-da-Silva P.
Published: J Respir Crit Care Med. 2020;(201:A2088).
Zamicastat decreases cardiac arrhythmias in a rat model of pulmonary arterial hypertension.
Pires N., Igreja B., Magalhães L., Bonifácio M.J., Chevalier E., Soares-da-Silva P.
Published: Pulmonary Hypertension. 2020.
BIA 5-1058 is a new noncompetitive dopamine-β-hydroxylase inhibitor.
Bonifacio M.J., Sousa F., Igreja B., Loureiro A.I., Wright L.C., Soares-da-Silva P.
Published: Proceedings of the British Pharmacological Society. 2012.
In vitro Species Different Metabolism and CYP Phenotyping of Zamicastast.
Loureiro A.I., Rebouta J., Bonifácio M.J., Soares-da-Silva P.
Published: FASEB J. 2020;34(S1):1–1.
A Double-Blind, Randomised, Placebo-Controlled, Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Zamicastat, in Healthy Male Volunteers.
Magalhães L., Rocha F., Falcão A., Gama H., Soares-da-Silva P.
Published: American Journal of Respiratory and Critical Care Medicine. 2020;201:A3816.
A Randomized, Double-Blind, Placebo-Controlled and Open-Label, Active-Controlled, 4-Period Crossover Trial to Evaluate the Effect of Zamicastat on Cardiac Repolarization in Healthy Adult Males and Females Under Fed Conditions.
Gama H., Magalhães L., Santos A., Soares-da-Silva P.
American Journal of Respiratory and Critical Care Medicine. 2020;201:A3815.
Drug-drug interaction study between zamicastat and bosentan in healthy subjects.
Guimarães A., Santos A., Ferreira J., Magalhães L., Gama H., Soares da Silva P.
Chest. 2020;157(6):A382.
Drug-drug interaction study between zamicastat and sildenafil in healthy subjects.
Santos A., Ferreira J., Gama H., Magalhães P. Soares -da-Silva P.
European Respiratory Journal 2020 56: 1458.
Drug-drug interaction study between zamicastat and treprostinil in healthy subjects.
Magalhães L., Guimarães A.M.R., Gana H., Magalhães P., Soares-da-Silva P.
American Journal of Respiratory and Critical Care Medicine 2021;203:A3615.